AmyPore is proud to announce that the team of Professor Jacques Fantini, co-inventor with Professor Nouara Yahi of the AmyP53 solution, has just published a major scientific article that opens a new therapeutic field for many diseases without solutions.
This article explains how to treat diseases involving a category of proteins called IDP (Intrinsically Disordered Proteins) with a new therapeutic class of peptides, adaptive peptides.
This original and disruptive solution was inaugurated by AmyPore with the peptide AmyP53, which targets a neurotoxic mechanism common to Alzheimer’s and Parkinson’s diseases.
This article was published by Pharmacology and Therapeutics, one of the best journals in these scientific fields worldwide.
Reference :
Conformationally adaptive therapeutic peptides for diseases caused by intrinsically disordered proteins (IDPs). New paradigm for drug discovery: Target the target, not the arrow
Jacques Fantini , Fodil Azzaz , Coralie Di Scala , Anaïs Aulas , Henri Chahinian , Nouara Yahi
Pharmacology & Therapeutics 2025
https://www.sciencedirect.com/science/article/pii/S0163725825000099
